Bone Marrow Concentrate (BMC) Injections for Knee Pain | Elite Pain & Health – Oklahoma

Bone Marrow Concentrate (BMC) Injections for Knee Pain

For patients with advanced knee arthritis or tissue degeneration who want to avoid or delay joint replacement, bone marrow concentrate (BMC) injections offer a biologic alternative that harnesses the body’s own regenerative potential.

At Elite Pain & Health – Oklahoma, Dr. Keley John Booth, MD performs image-guided BMC procedures that use autologous (your own) bone marrow rich in stem and progenitor cells to stimulate healing, reduce inflammation, and restore joint integrity. This therapy supports natural tissue repair when traditional medications or PRP injections are no longer enough.

Why It Helps

Bone marrow contains a complex mixture of mesenchymal stem cells (MSCs), platelets, and growth factors that orchestrate the body’s healing response. When concentrated and injected into damaged joint tissues, these biologic components help:

• Regenerate cartilage and connective tissue

• Reduce chronic inflammation in arthritic joints

• Stimulate repair of tendons, ligaments, and bone

• Improve lubrication and mobility

• Slow degeneration and delay surgical intervention

BMC therapy is especially effective for moderate-to-severe osteoarthritis*,* meniscal deficiency*, and* chronic cartilage lesions that have not improved with conservative treatment.

What to Expect

BMC therapy is performed in the clinic under sterile, image-guided conditions and typically takes 90 minutes.

Step-by-Step Process

Bone Marrow Aspiration

A small sample of bone marrow is drawn from the back of your pelvis (iliac crest) under local anesthesia.

Processing & Concentration

The sample is spun in a medical-grade centrifuge to isolate a cell-rich concentrate containing stem and regenerative cells.

Injection Preparation

The BMC is refined to an optimized concentration and combined with platelet-derived plasma if indicated.

Image-Guided Injection

Using ultrasound or fluoroscopy, Dr. Booth precisely injects the BMC into targeted areas of the knee cartilage surfaces, meniscus, or subchondral bone.

Patients typically walk out of the office after the procedure, experiencing mild stiffness or pressure at the injection or aspiration site for 24–48 hours.

How It’s Diagnosed

Before recommending BMC therapy, Dr. Booth performs a comprehensive image-guided diagnostic evaluation to confirm candidacy. This includes:

• MRI or ultrasound to assess cartilage, bone marrow, and soft-tissue condition

• Physical examination for mechanical alignment and stability

• Review of previous treatments (PRP, viscosupplementation, corticosteroids)

• Screening labs to ensure overall health and suitability

This precision-based approach ensures that BMC is applied to the right patient, at the right stage, for optimal outcome.

Learn more about knee diagnoses and knee symptoms.

Conservative & Regenerative Treatment Plan

BMC injections are often considered the next step beyond PRP when greater biologic support is needed.

 Dr. Booth typically integrates BMC therapy into a comprehensive plan that includes:

• Activity modification

• Bracing & support devices

• Weight management

• Targeted rehabilitation and strengthening

• Periodic biologic follow-up imaging

The entire procedure takes 20–30 minutes, and patients typically walk out immediately afterward.

Aftercare

• A thin radiofrequency probe is placed next to each targeted genicular nerve.

• Limit high-impact activity for 5–7 days.

• Resume gradual exercise and therapy as tolerated.

• Multiple nerve sites may be treated to ensure comprehensive coverage.

Healing continues over 3–6 months, as regenerative cells rebuild and remodel joint tissue.

When to Seek Care

You may be a candidate for BMC therapy if you:

• Have moderate to advanced arthritis not improved by PRP or HA injections

• Want to delay or avoid knee replacement surgery

• Experience chronic pain, stiffness, or swelling from cartilage damage

• Prefer autologous, non-surgical regenerative treatment

At Elite Pain & Health – Oklahoma*, each injection is performed under real-time imaging to maximize accuracy and safety.*

Take the Next Step

BMC therapy can help rebuild, not just relieve, your knee pain naturally and precisely.